Mal-PEG8-t-butyl ester

Modify Date: 2024-01-10 18:47:48

Mal-PEG8-t-butyl ester Structure
Mal-PEG8-t-butyl ester structure
Common Name Mal-PEG8-t-butyl ester
CAS Number 2055048-43-4 Molecular Weight 577.66
Density N/A Boiling Point N/A
Molecular Formula C27H47NO12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-PEG8-t-butyl ester


Mal-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-PEG8-Boc
Synonym More Synonyms

 Mal-PEG8-t-butyl ester Biological Activity

Description Mal-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C27H47NO12
Molecular Weight 577.66

 Synonyms

MFCD30458029