Mcl1-IN-26

Modify Date: 2024-04-08 18:28:03

Mcl1-IN-26 Structure
Mcl1-IN-26 structure
Common Name Mcl1-IN-26
CAS Number 2056238-04-9 Molecular Weight 826.45
Density N/A Boiling Point N/A
Molecular Formula C45H52ClN5O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mcl1-IN-26


A novel potent, selective Mcl-1 inhibitor with IC50 of <3 nM in FRET assays; displays >1,000-fold selectivity over Bcl-2 and Bcl-xL; induces cleaved caspase-3 in MV4-11 cells with IC50 of 3.78 uM.

 Names

Name Mcl1-IN-26

 Mcl1-IN-26 Biological Activity

Description A novel potent, selective Mcl-1 inhibitor with IC50 of <3 nM in FRET assays; displays >1,000-fold selectivity over Bcl-2 and Bcl-xL; induces cleaved caspase-3 in MV4-11 cells with IC50 of 3.78 uM.
References References 1. Johannes JW, et al. ACS Med Chem Lett. 2016 Dec 27;8(2):239-244. View Related Products by Target Bcl-2

 Chemical & Physical Properties

Molecular Formula C45H52ClN5O6S
Molecular Weight 826.45
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