MS-377
Modify Date: 2023-09-07 19:38:59
MS-377 structure
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Common Name | MS-377 | ||
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| CAS Number | 206862-30-8 | Molecular Weight | 351.875 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H26ClN3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MS-377MS-377 is a potent, selective sigma-1 receptor ligand with Kd of 15.2 nM, showed anti-phencyclidine (PCP), anti-dopaminergic and anti-serotonergic activities; markedly increases dopamine and serotonin release in the medial prefrontal cortex, significantly attenuates the effect of PCP in rat brain. Schizophrenia Discontinued |
| Name | MS-377 |
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| Description | MS-377 is a potent, selective sigma-1 receptor ligand with Kd of 15.2 nM, showed anti-phencyclidine (PCP), anti-dopaminergic and anti-serotonergic activities; markedly increases dopamine and serotonin release in the medial prefrontal cortex, significantly attenuates the effect of PCP in rat brain. Schizophrenia Discontinued |
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| References | References 1. Takahashi S, et al. Psychopharmacology (Berl). 1999 Aug;145(3):295-302. 2. Karasawa J, et al. Eur J Pharmacol. 2000 Jul 14;400(1):51-7. 3. Yamada S, et al. Eur J Pharmacol. 2000 Aug 25;402(3):251-4. 4. Takahashi S, et al. Eur J Pharmacol. 2001 Sep 21;427(3):211-9. View Related Products by Target Sigma Receptor Schizophrenia |
| Molecular Formula | C18H26ClN3O2 |
|---|---|
| Molecular Weight | 351.875 |