MS 15203 structure
|
Common Name | MS 15203 | ||
---|---|---|---|---|
CAS Number | 73912-52-4 | Molecular Weight | 249.21900 | |
Density | 1.42g/cm3 | Boiling Point | 561.3ºC at 760 mmHg | |
Molecular Formula | C12H11NO5 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 293.2ºC |
Use of MS 15203MS15203 is a potent and selective GPR171 agonist. MS15203 increases food intake and body weight. MS15203 increases neuronal activity. MS15203 significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP[1]. |
Name | chembrdg-bb 5186719 |
---|---|
Synonym | More Synonyms |
Description | MS15203 is a potent and selective GPR171 agonist. MS15203 increases food intake and body weight. MS15203 increases neuronal activity. MS15203 significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP[1]. |
---|---|
Related Catalog | |
In Vitro | MS15203 (MS0015203) dose-dependently increases [[35]S]GTPγS binding and inhibits adenylyl cyclase activity in rat hypothalamic membranes[1]. |
In Vivo | MS15203 (MS0015203) (3 mg/kg; i.p.) causes an increase in neuronal activity within cells containing GPR171 in the PVN[1]. .MS15203 (3 mg/kg; i.p.) significantly increases food intake at 4 and 8 hours[1]. MS15203 (3 mg/kg; i.p.) significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP[1]. |
References |
Density | 1.42g/cm3 |
---|---|
Boiling Point | 561.3ºC at 760 mmHg |
Molecular Formula | C12H11NO5 |
Molecular Weight | 249.21900 |
Flash Point | 293.2ºC |
Exact Mass | 249.06400 |
PSA | 103.70000 |
LogP | 1.67060 |
Index of Refraction | 1.639 |
HS Code | 2924199090 |
---|
~82% MS 15203 CAS#:73912-52-4 |
Literature: Ezhova, N. M.; Kulina, E. A.; Kuznetsova, N. N. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1980 , vol. 29, # 2 p. 267 - 269 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1980 , # 2 p. 352 - 354 |
Precursor 2 | |
---|---|
DownStream 0 |
HS Code | 2924199090 |
---|---|
Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
MFCD00434754 |