MRT68921 hydrochloride

Modify Date: 2024-04-08 14:50:17

MRT68921 hydrochloride Structure
MRT68921 hydrochloride structure
Common Name MRT68921 hydrochloride
CAS Number 2070014-87-6 Molecular Weight 471.038
Density N/A Boiling Point N/A
Molecular Formula C25H35ClN6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MRT68921 hydrochloride


MRT68921 hydrochloride is a potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively.

 Names

Name MRT68921 hydrochloride
Synonym More Synonyms

 MRT68921 hydrochloride Biological Activity

Description MRT68921 hydrochloride is a potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively.
Related Catalog
References

[1]. Petherick KJ, et al. Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy. J Biol Chem. 2015 May 1;290(18):11376-83.  

 Chemical & Physical Properties

Molecular Formula C25H35ClN6O
Molecular Weight 471.038
Exact Mass 470.256073

 Synonyms

Cyclobutanecarboxamide, N-[3-[[5-cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]-, hydrochloride (1:1)
N-[3-({5-Cyclopropyl-2-[(2-methyl-1,2,3,4-tetrahydro-6-isoquinolinyl)amino]-4-pyrimidinyl}amino)propyl]cyclobutanecarboxamide hydrochloride (1:1)
MFCD30187515
BS-16452