N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)

Modify Date: 2024-01-07 12:33:15

N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) Structure
N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) structure
Common Name N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)
CAS Number 2093152-79-3 Molecular Weight 871.06
Density N/A Boiling Point N/A
Molecular Formula C40H78N4O16 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)


N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester)

 N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) Biological Activity

Description N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C40H78N4O16
Molecular Weight 871.06

 Safety Information

Hazard Codes Xi
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