N-(Azido-PEG4)-N-bis(PEG4-acid) HCl

Modify Date: 2024-01-11 03:29:54

N-(Azido-PEG4)-N-bis(PEG4-acid) HCl Structure
N-(Azido-PEG4)-N-bis(PEG4-acid) HCl structure
Common Name N-(Azido-PEG4)-N-bis(PEG4-acid) HCl
CAS Number 2093152-80-6 Molecular Weight 758.85
Density N/A Boiling Point N/A
Molecular Formula C32H62N4O16 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Azido-PEG4)-N-bis(PEG4-acid) HCl


N-(Azido-PEG4)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(Azido-PEG4)-N-bis(PEG4-acid)

 N-(Azido-PEG4)-N-bis(PEG4-acid) HCl Biological Activity

Description N-(Azido-PEG4)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C32H62N4O16
Molecular Weight 758.85
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