CYP17-IN-1

Modify Date: 2024-01-02 22:11:13

CYP17-IN-1 structure	Common Name	CYP17-IN-1
	CAS Number	2093317-51-0	Molecular Weight	312.40
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₇FN₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CYP17-IN-1

CYP17-IN-1 (compound 9c) is a potent and orally active CYP17 inhibitor against rat and human CYP17 with IC50s of 15.8 and 20.1 nM[1].

Name	CYP17-IN-1

Description	CYP17-IN-1 (compound 9c) is a potent and orally active CYP17 inhibitor against rat and human CYP17 with IC50s of 15.8 and 20.1 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450
Target	IC50: 15.8 nM (Rat CYP17), 20.1 nM (Human CYP17)[1]
In Vitro	CYP17-IN-1 (compound 9c) exhibits an IC50 value of 8.5 µM against CYP3A4[1].
In Vivo	CYP17-IN-1 (compound 9c) reduces plasma testosterone level in a dose-dependent manner in Sprague-Dawley rats[1].
References	[1]. Wang M, et al. Discovery of novel 1,2,3,4-tetrahydrobenzo[4, 5]thieno[2, 3-c]pyridine derivatives as potent and selective CYP17 inhibitors. Eur J Med Chem. 2017 May 26;132:157-172.

Molecular Formula	C₁₈H₁₇FN₂S
Molecular Weight	312.40

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CYP17-IN-1
Price: Click To Check
Purity: 99.17%
Delivery: 10 Day
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