ROX-SE

Modify Date: 2024-01-08 16:52:14

ROX-SE Structure
ROX-SE structure
Common Name ROX-SE
CAS Number 209734-74-7 Molecular Weight 631.67400
Density N/A Boiling Point N/A
Molecular Formula C37H33N3O7 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of ROX-SE


5-Carboxy-X-rhodamin N-succinimidyl ester is a labeling reagent. 5-Carboxy-X-rhodamin N-succinimidyl ester can be used in the preparation of charge-modified dye-labeled Dideoxynucleotide Triphosphates (ddNTP) to "direct-load" DNA sequencing[1].

 Names

Name 5-Carboxy-X-rhodamine N-succinimidyl ester
Synonym More Synonyms

 ROX-SE Biological Activity

Description 5-Carboxy-X-rhodamin N-succinimidyl ester is a labeling reagent. 5-Carboxy-X-rhodamin N-succinimidyl ester can be used in the preparation of charge-modified dye-labeled Dideoxynucleotide Triphosphates (ddNTP) to "direct-load" DNA sequencing[1].
Related Catalog
References

[1]. Finn PJ, Sun L, Nampalli S, Xiao H, Nelson JR, Mamone JA, Grossmann G, Flick PK, Fuller CW, Kumar S. Synthesis and application of charge-modified dye-labeled dideoxynucleoside-5'-triphosphates to 'direct-load' DNA sequencing. Nucleic Acids Res. 2002 Jul 1;30(13):2877-85.

 Chemical & Physical Properties

Molecular Formula C37H33N3O7
Molecular Weight 631.67400
Exact Mass 631.23200
PSA 123.43000
LogP 4.58390
Storage condition -20°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport

 Precursor & DownStream

Precursor  2

DownStream  0

 Articles9

More Articles
High-resolution liquid chromatography of fluorescent dye-labeled nucleic acids.

Anal. Biochem. 223 , 39, (1994)

Using 100 mM of triethylammonium acetate as ion-pairing reagent, phosphodiester oligonucleotides labeled fluorescently at their 5' terminus could be separated successfully on alkylated nonporous 2.3-m...

DNA sequencing with dye-labeled terminators and T7 DNA polymerase: effect of dyes and dNTPs on incorporation of dye-terminators and probability analysis of termination fragments.

Nucleic Acids Res. 20 , 2471, (1992)

The incorporation of fluorescently labeled dideoxynucleotides by T7 DNA polymerase is optimized by the use of Mn2+, fluorescein analogs and four 2'-deoxyribonucleoside 5'-O-(1-thiotriphosphates) (dNTP...

Synthesis and application of charge-modified dye-labeled dideoxynucleoside-5'-triphosphates to 'direct-load' DNA sequencing.

Nucleic Acids Res. 30 , 2877, (2002)

A novel series of charge-modified, dye-labeled 2',3'-dideoxynucleoside-triphosphate terminators were synthesized and evaluated as reagents for DNA sequencing. These terminators possess an advantage ov...

 Synonyms

5-carboxy-X-rhodamine succinimidyl ester
5-ROX,SE [5-Carboxy-X-rhodamine,succinimidyl ester]