N-(Propargyl-PEG2)-N-bis(PEG1-alcohol)

Modify Date: 2024-01-08 19:02:33

N-(Propargyl-PEG2)-N-bis(PEG1-alcohol) Structure
N-(Propargyl-PEG2)-N-bis(PEG1-alcohol) structure
Common Name N-(Propargyl-PEG2)-N-bis(PEG1-alcohol)
CAS Number 2100306-62-3 Molecular Weight 319.39
Density N/A Boiling Point N/A
Molecular Formula C15H29NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Propargyl-PEG2)-N-bis(PEG1-alcohol)


Propargyl-PEG2-N-bis(PEG2) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG2-N-bis(PEG2)
Synonym More Synonyms

 N-(Propargyl-PEG2)-N-bis(PEG1-alcohol) Biological Activity

Description Propargyl-PEG2-N-bis(PEG2) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C15H29NO6
Molecular Weight 319.39

 Synonyms

MFCD30723221
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