Methyltetrazine-amido-PEG7-azide

Modify Date: 2024-01-23 12:03:52

Methyltetrazine-amido-PEG7-azide Structure
Methyltetrazine-amido-PEG7-azide structure
Common Name Methyltetrazine-amido-PEG7-azide
CAS Number 2112731-46-9 Molecular Weight 606.67
Density N/A Boiling Point N/A
Molecular Formula C27H42N8O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Methyltetrazine-amido-PEG7-azide


Methyltetrazine-amido-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Methyltetrazine-amido-PEG7-azide

 Methyltetrazine-amido-PEG7-azide Biological Activity

Description Methyltetrazine-amido-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C27H42N8O8
Molecular Weight 606.67