10,11-Dehydrocurvularin

Modify Date: 2024-01-02 22:17:29

10,11-Dehydrocurvularin structure	Common Name	10,11-Dehydrocurvularin
	CAS Number	21178-57-4	Molecular Weight	290.31100
	Density	1.225 g/cm3	Boiling Point	576.3ºC at 760 mm
	Molecular Formula	C₁₆H₁₈O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	216.7ºC

Use of 10,11-Dehydrocurvularin

10,11-Dehydrocurvularin is a prevalent fungal phytotoxin and an antibiotic. 10,11-Dehydrocurvularin is a strong activator of the heat shock response. 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity[1][2].

Name	(5S,9E)-13,15-dihydroxy-5-methyl-4-oxabicyclo[10.4.0]hexadeca-1(12),9,13,15-tetraene-3,11-dione
Synonym	More Synonyms

Description	10,11-Dehydrocurvularin is a prevalent fungal phytotoxin and an antibiotic. 10,11-Dehydrocurvularin is a strong activator of the heat shock response. 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> TGF-beta/Smad Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Signaling Pathways >> TGF-beta/Smad >> TGF-beta/Smad Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
References	[1]. Xu Y, et al. Characterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus. Appl Environ Microbiol. 2013 Mar;79(6):2038-47. [2]. Cochrane RV, et al. Comparison of 10,11-Dehydrocurvularin Polyketide Synthases from Alternaria cinerariae and Aspergillus terreus Highlights Key Structural Motifs. Chembiochem. 2015 Nov;16(17):2479-83.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Stem Cell/Wnt >> TGF-beta/Smad

Signaling Pathways >> Metabolic Enzyme/Protease >> HSP

Signaling Pathways >> TGF-beta/Smad >> TGF-beta/Smad

Research Areas >> Infection

Signaling Pathways >> Cell Cycle/DNA Damage >> HSP

References

[1]. Xu Y, et al. Characterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus. Appl Environ Microbiol. 2013 Mar;79(6):2038-47.

[2]. Cochrane RV, et al. Comparison of 10,11-Dehydrocurvularin Polyketide Synthases from Alternaria cinerariae and Aspergillus terreus Highlights Key Structural Motifs. Chembiochem. 2015 Nov;16(17):2479-83.

Density	1.225 g/cm3
Boiling Point	576.3ºC at 760 mm
Molecular Formula	C₁₆H₁₈O₅
Molecular Weight	290.31100
Flash Point	216.7ºC
Exact Mass	290.11500
PSA	83.83000
LogP	2.49480
Vapour Pressure	7.02E-14mmHg at 25°C
Index of Refraction	1.555

HS Code	2932999099

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

trans-dehydrocurvularin

E-dehydrocurvularin

10,11-dehydrocurvularin

8-dehydrocurvularin

Dehydrocurvularin

AmbotzLS-1091

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 10,11-dehydro Curvularin
Price: Click To Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: 10,11-Dehydrocurvularin
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ALPHA,BETA-DEHYDROCURVULARIN
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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10,11-Dehydrocurvularin

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