Pa 155A

Modify Date: 2024-01-05 10:18:42

Pa 155A structure	Common Name	Pa 155A
	CAS Number	21200-24-8	Molecular Weight	257.288
	Density	1.4±0.1 g/cm3	Boiling Point	420.8±37.0 °C at 760 mmHg
	Molecular Formula	C₁₄H₁₅N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	208.3±26.5 °C

Use of Pa 155A

Indolmycin (TAK-083), an antibiotic, is a competitive inhibitor of prokaryotic tryptophanyl-tRNA ligase (TrpS). Indolmycin (TAK-083) possesses both anti-viral and anti-bacterial activity[1][2][3].

Name	indolmycin
Synonym	More Synonyms

Description	Indolmycin (TAK-083), an antibiotic, is a competitive inhibitor of prokaryotic tryptophanyl-tRNA ligase (TrpS). Indolmycin (TAK-083) possesses both anti-viral and anti-bacterial activity[1][2][3].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Indolmycin was bacteriostatic and demonstrated good activity against MSSA (methicillinsusceptible Staphylococcus aureus), MRSA (methicillin-resistant S. aureus) and VISA (vancomycinintermediate S. aureus), including strains resistant to mupirocin or fusidic acid. Indolmycin MICs for 20 strains ranged from 8 to 32 mg/L, whereas asingle strain exhibited high-level resistance (MIC 128 mg/L)[2].
References	[1]. R G Werner, et al. Indolmycin inhibits prokaryotic tryptophanyl-tRNA ligase. Eur J Biochem. 1976 Sep;68(1):1-3. [2]. Julian G Hurdle, et al. Anti-staphylococcal activity of indolmycin, a potential topical agent for control of staphylococcal infections. J Antimicrob Chemother. 2004 Aug;54(2):549-52. [3]. M R Harnden, et al. Thiazolinone analogues of indolmycin with antiviral and antibacterial activity. J Med Chem. 1978 Jan;21(1):82-7.

Density	1.4±0.1 g/cm3
Boiling Point	420.8±37.0 °C at 760 mmHg
Molecular Formula	C₁₄H₁₅N₃O₂
Molecular Weight	257.288
Flash Point	208.3±26.5 °C
Exact Mass	257.116425
PSA	69.97000
LogP	1.53
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.670

HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

[S-(R*,S*)]-5-[1-(1H-Indol-3-yl)ethyl]-2-(methylamino)-4(5H)-oxazolone

(1R,5S)-(-)-5-(1-Indol-3-ylethyl)-2-(methylamino)-2-oxazolin-4-one

(5S)-5-[(1R)-1-(1H-Indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one

Indolemycin

4(5H)-Oxazolone, 5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-, (5S)-

2-Methylamino-5a-(b-indolyl)ethyl-2-oxazolin-4-one

Pa 155A

indolmycin

2-Oxazolin-4-one,5-(1-indol-3-ylethyl)-2-(methylamino)-,(1R,5S)-(-)

4(5H)-Oxazolone,5-(1-(1H-indol-3-yl)ethyl)-2-(methylamino)-,(S-(R*,S*))

PA 155 A

5-(1-Indol-3-ylethyl)-2-(methylamino)-2-oxazolin-4-one

Indomycin

(5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4-one

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Indolmycin
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Indolmycin
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Pa 155A

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.