Aurora A/PKC-IN-1
Modify Date: 2024-01-09 23:24:55
Aurora A/PKC-IN-1 structure
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Common Name | Aurora A/PKC-IN-1 | ||
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| CAS Number | 2143100-98-3 | Molecular Weight | 464.24 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H14N6OSe2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Aurora A/PKC-IN-1Aurora A/PKC-IN-1 (Compound 2e) is a potent dual inhibitor of Aurora A (AurA) and PKC (α, β1, β2, and θ) kinases with IC50s of 6.9 nM and 16.9 nM for AurA and PKCα, respectively. Aurora A/PKC-IN-1 has antiproliferative activity in breast cancer cells and antimetastatic activity[1]. |
| Name | Aurora A/PKC-IN-1 |
|---|
| Description | Aurora A/PKC-IN-1 (Compound 2e) is a potent dual inhibitor of Aurora A (AurA) and PKC (α, β1, β2, and θ) kinases with IC50s of 6.9 nM and 16.9 nM for AurA and PKCα, respectively. Aurora A/PKC-IN-1 has antiproliferative activity in breast cancer cells and antimetastatic activity[1]. |
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| Related Catalog | |
| Target |
Aurora A:6.9 nM (IC50) PKCα:16.9 nM (IC50) |
| References |
| Molecular Formula | C16H14N6OSe2 |
|---|---|
| Molecular Weight | 464.24 |