[Pyr1] -Apelin 13 structure
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Common Name | [Pyr1] -Apelin 13 | ||
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CAS Number | 217082-60-5 | Molecular Weight | 1532.81 | |
Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C70H109N21O16S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of [Pyr1] -Apelin 13[Pyr1]-Apelin-13 is a highly potent, selective endogenous apelin receptor (APJ) agonist. |
Name | [Pyr1]-Apelin-13 |
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Synonym | More Synonyms |
Description | [Pyr1]-Apelin-13 is a highly potent, selective endogenous apelin receptor (APJ) agonist. |
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Related Catalog | |
In Vitro | [Pyr1]-apelin-13 encapsulation in lipoPEG particles (lipoPEG-PA13) results in sustained and extended drug release under physiological conditions[1]. |
In Vivo | [Pyr1]-apelin-13 nanocarriers in a mouse model of pressure-overload induced heart failure demonstrate a sustainable long-term effect of [Pyr1]-apelin-13 in preventing cardiac dysfunction[1]. [Pyr1] apelin-13 (1, 5 μg) improves locomotor activity and reduces pain symptoms, cavity size and caspase-3 levels in rats. [Pyr1] apelin-13 (1, 5 μg) significantly increases thermal paw withdrawal latency. [Pyr1] apelin-13 in 5 μg dose also produces significant attenuation in paw withdrawal threshold compared to SCI animals from the second week post SCI[2]. |
References |
Density | 1.5±0.1 g/cm3 |
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Molecular Formula | C70H109N21O16S |
Molecular Weight | 1532.81 |
PSA | 613.26000 |
LogP | -3.42 |
Index of Refraction | 1.696 |
Storage condition | -15°C |
PGLU-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE |
pQRPRLSHKGPMPF |
Deltorphin I |
PYR-RPRLSHKGPMPF-OH |
GLP-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE |
5-Oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine |
L-Phenylalanine, 5-oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl- |
PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE |
pyroglutamyl apelin-13 |