Apelin 13

Modify Date: 2024-01-13 16:55:44

Apelin 13 structure	Common Name	Apelin 13
	CAS Number	217082-58-1	Molecular Weight	1550.829
	Density	1.5±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₆₉H₁₁₁N₂₃O₁₆S	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of Apelin 13

Apelin-13 is the endogenous ligand of the orphan G protein-coupled receptor APJ, activates APJ receptor with an EC50 value of 0.37 nM in CHO cells[1][2].

Name	gln-arg-pro-arg-leu-ser-his-lys-gly-pro-met-pro-phe
Synonym	More Synonyms

Description	Apelin-13 is the endogenous ligand of the orphan G protein-coupled receptor APJ, activates APJ receptor with an EC50 value of 0.37 nM in CHO cells[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Tatemoto, K., Hosoya, M., Habata, Y., et al. Isolation and characterizaton of a novel endogenous peptide ligand for the human APJ receptor. Biochemical and Biophysical Research Communications 251, 471-476 (1998). [2]. Li M,et al. Apelin 13 ameliorates metabolic and cardiovascular disorders in a rat model of type 2 diabetes with a high fat diet. Mol Med Rep. 2018 Dec;18(6):5784-5790.

Description

Apelin-13 is the endogenous ligand of the orphan G protein-coupled receptor APJ, activates APJ receptor with an EC50 value of 0.37 nM in CHO cells[1][2].

Related Catalog

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

References

[1]. Tatemoto, K., Hosoya, M., Habata, Y., et al. Isolation and characterizaton of a novel endogenous peptide ligand for the human APJ receptor. Biochemical and Biophysical Research Communications 251, 471-476 (1998).

[2]. Li M,et al. Apelin 13 ameliorates metabolic and cardiovascular disorders in a rat model of type 2 diabetes with a high fat diet. Mol Med Rep. 2018 Dec;18(6):5784-5790.

Density	1.5±0.1 g/cm3
Molecular Formula	C₆₉H₁₁₁N₂₃O₁₆S
Molecular Weight	1550.829
Exact Mass	1549.829956
PSA	653.27000
LogP	-3.42
Index of Refraction	1.688
Storage condition	−20°C
Water Solubility	Soluble in PBS (pH 7.2) at approximately 10 mg/ml.

WGK Germany	3

APELIN-13

L-Phenylalanine, L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-

Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe ((2) Due to the presence of a Gln in N-terMinal position this peptide can contain the pyroglutaMic forM)

APELIN-13 (HUMAN,BOVINE,MOUSE,RAT)

Apelin-13,human,bovine,mouse,rat (2)

APELIN-13 (HUMAN,BOVINE)

L-Glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine

apelin-13 trifluoroacetate salt

QRPRLSHKGPMPF

PREPRO-65-77-APELIN

MFCD02094627