Bis(m-PEG4)-N-OH

Modify Date: 2024-01-17 09:46:12

Bis(m-PEG4)-N-OH Structure
Bis(m-PEG4)-N-OH structure
Common Name Bis(m-PEG4)-N-OH
CAS Number 2182601-79-0 Molecular Weight 413.50
Density N/A Boiling Point N/A
Molecular Formula C18H39NO9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis(m-PEG4)-N-OH


Bis(m-PEG4)-N-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bis(m-PEG4)-N-OH

 Bis(m-PEG4)-N-OH Biological Activity

Description Bis(m-PEG4)-N-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C18H39NO9
Molecular Weight 413.50
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