NH-bis(m-PEG4)
Modify Date: 2024-01-31 18:26:40
NH-bis(m-PEG4) structure
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Common Name | NH-bis(m-PEG4) | ||
|---|---|---|---|---|
| CAS Number | 123852-08-4 | Molecular Weight | 397.50400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H39NO8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NH-bis(m-PEG4)NH-bis(m-PEG4) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-N-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethyl]ethanamine |
|---|---|
| Synonym | More Synonyms |
| Description | NH-bis(m-PEG4) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C18H39NO8 |
|---|---|
| Molecular Weight | 397.50400 |
| Exact Mass | 397.26800 |
| PSA | 85.87000 |
| LogP | 0.35930 |
|
~94%
NH-bis(m-PEG4) CAS#:123852-08-4 |
| Literature: Selve, Claude; Moumni, El Mostafa; Delpuech, Jean-Jacques Journal of the Chemical Society, Chemical Communications, 1987 , # 19 p. 1437 - 1438 |
|
~%
NH-bis(m-PEG4) CAS#:123852-08-4 |
| Literature: Selve; Ravey; Stebe; El Moudjahid; Moumni; Delpuech Tetrahedron, 1991 , vol. 47, # 3 p. 411 - 428 |
|
~%
NH-bis(m-PEG4) CAS#:123852-08-4 |
| Literature: Selve; Ravey; Stebe; El Moudjahid; Moumni; Delpuech Tetrahedron, 1991 , vol. 47, # 3 p. 411 - 428 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| N,N-bis(tetraethyleneglycol-monomethylether)amine |
| N,N-bis(tetraoxyethylenemonomethyl ether)amine |
| 2,5,8,11-Tetraoxatridecan-13-amine,N-3,6,9,12-tetraoxatridec-1-yl |
| bis-[2-[2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy]-ethyl]-amine |