Bis-(m-PEG4)-amidohexanoic acid

Modify Date: 2025-08-27 12:58:13

Bis-(m-PEG4)-amidohexanoic acid Structure
Bis-(m-PEG4)-amidohexanoic acid structure
Common Name Bis-(m-PEG4)-amidohexanoic acid
CAS Number 2353409-74-0 Molecular Weight 582.68
Density N/A Boiling Point N/A
Molecular Formula C26H50N2O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-(m-PEG4)-amidohexanoic acid


Bis-(m-PEG4)-amidohexanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bis-(m-PEG4)-amidohexanoic acid

 Bis-(m-PEG4)-amidohexanoic acid Biological Activity

Description Bis-(m-PEG4)-amidohexanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C26H50N2O12
Molecular Weight 582.68
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