N-(acid-PEG3)-N-bis(PEG3-azide)

Modify Date: 2024-01-05 17:14:24

N-(acid-PEG3)-N-bis(PEG3-azide) Structure
N-(acid-PEG3)-N-bis(PEG3-azide) structure
Common Name N-(acid-PEG3)-N-bis(PEG3-azide)
CAS Number 2182602-17-9 Molecular Weight 623.70
Density N/A Boiling Point N/A
Molecular Formula C25H49N7O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(acid-PEG3)-N-bis(PEG3-azide)


N-(acid-PEG3)-N-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(acid-PEG3)-N-bis(PEG3-azide)

 N-(acid-PEG3)-N-bis(PEG3-azide) Biological Activity

Description N-(acid-PEG3)-N-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C25H49N7O11
Molecular Weight 623.70
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