N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester)

Modify Date: 2024-01-10 10:05:59

N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester) Structure
N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester) structure
Common Name N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester)
CAS Number 2112734-70-8 Molecular Weight 802.00
Density N/A Boiling Point N/A
Molecular Formula C38H75NO16 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Hydroxy-PEG3)-N-bis(PEG4-t-butyl ester)


N-(Hydroxy-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(Hydroxy-PEG3)-N-bis(PEG4-Boc)
Synonym More Synonyms

  Biological Activity

Description N-(Hydroxy-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C38H75NO16
Molecular Weight 802.00

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD30730366