LIMK1 and 2 dual inhibitor
Modify Date: 2024-01-10 12:39:55
LIMK1 and 2 dual inhibitor structure
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Common Name | LIMK1 and 2 dual inhibitor | ||
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| CAS Number | 2215049-71-9 | Molecular Weight | 610.63 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H21F3N6O3S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LIMK1 and 2 dual inhibitorLIMK1 and 2 dual inhibitor is a potent, selective LIMK1/2 inhibitor with IC50 of <10 nM for both, 15-fold selectivity over B-Raf (IC50=10-100 nM); inhibits p-c-ofilin at Ser3 site, suppresses cell proliferation of MV-411 cell of with IC50 of 1-5 uM. |
| Name | LIMK1 and 2 dual inhibitor |
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| Description | LIMK1 and 2 dual inhibitor is a potent, selective LIMK1/2 inhibitor with IC50 of <10 nM for both, 15-fold selectivity over B-Raf (IC50=10-100 nM); inhibits p-c-ofilin at Ser3 site, suppresses cell proliferation of MV-411 cell of with IC50 of 1-5 uM. |
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| References | References 1. US Patent WO 2018055097. View Related Products by Target LIM Kinase (LIMK) |
| Molecular Formula | C28H21F3N6O3S2 |
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| Molecular Weight | 610.63 |