Amino-PEG24-alcohol

Modify Date: 2024-01-20 18:45:33

Amino-PEG24-alcohol Structure
Amino-PEG24-alcohol structure
Common Name Amino-PEG24-alcohol
CAS Number 2226726-55-0 Molecular Weight 1074.29
Density N/A Boiling Point N/A
Molecular Formula C48H99NO24 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amino-PEG24-alcohol


Amino-PEG24-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Amino-PEG24-alcohol
Synonym More Synonyms

 Amino-PEG24-alcohol Biological Activity

Description Amino-PEG24-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C48H99NO24
Molecular Weight 1074.29

 Synonyms

MFCD21363266