TL 13-22

Modify Date: 2024-04-09 05:55:08

TL 13-22 structure	Common Name	TL 13-22
	CAS Number	2229036-65-9	Molecular Weight	947.50
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₅H₅₅ClN₁₀O₉S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TL 13-22

TL13-22 is a negative control for TL13-12 (HY-122582) and a potent ALK inhibitor with an IC50 of 0.54 nM. TL13-22 does not degrade ALK in cells[1].

Name	TL13-22

Description	TL13-22 is a negative control for TL13-12 (HY-122582) and a potent ALK inhibitor with an IC50 of 0.54 nM. TL13-22 does not degrade ALK in cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK
Target	IC50: 0.54 nM (ALK)[1]
In Vitro	TL13-22 prompts the degradation of additional kinases including Aurora A, FER, PTK2, and RPS6KA1 with IC50 values of 11.3 nM, 5.74 nM, 18.4 nM, and 65.9 nM, respectively[1].
References	[1]. Chelsea E Powell, et al. Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK). J Med Chem. 2018 May 10;61(9):4249-4255.

Molecular Formula	C₄₅H₅₅ClN₁₀O₉S
Molecular Weight	947.50

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TL 13-22
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: TL13-22
Price: $550.0/5mg $800.0/10mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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