FKBP12 Ligand

Modify Date: 2025-09-04 13:49:07

FKBP12 Ligand Structure
FKBP12 Ligand structure
Common Name FKBP12 Ligand
CAS Number 2230613-03-1 Molecular Weight 693.78
Density N/A Boiling Point N/A
Molecular Formula C38H47NO11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FKBP12 Ligand


PROTAC FKBP12 Ligand 1 can be used for synthesis of dTAG molecules. dTAG molecules selectively degrade FKBP12.

 Names

Name PROTAC FKBP12 Ligand 1

 FKBP12 Ligand Biological Activity

Description PROTAC FKBP12 Ligand 1 can be used for synthesis of dTAG molecules. dTAG molecules selectively degrade FKBP12.
Related Catalog
In Vitro FKBP12 recruits CRBN1 by heterobifunctional degraders.
References

[1]. Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441.

 Chemical & Physical Properties

Molecular Formula C38H47NO11
Molecular Weight 693.78
InChIKey UYXSZUBFOQLRNQ-BTIIJPOSSA-N
SMILES CCC(C(=O)N1CCCCC1C(=O)OC(CCc1ccc(OC)c(OC)c1)c1ccccc1OCC(=O)O)c1cc(OC)c(OC)c(OC)c1
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