KRAS inhibitor-17

Modify Date: 2024-01-10 21:58:45

KRAS inhibitor-17 structure	Common Name	KRAS inhibitor-17
	CAS Number	2230873-65-9	Molecular Weight	466.36
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₈Cl₂FN₃O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of KRAS inhibitor-17

KRAS inhibitor-17 (compound 3-9) is a potent KRAS G12C inhibitor with an IC50 of 3.37 µM. KRAS inhibitor-17 shows p-ERK inhibition activities with IC50s of 9.25, >33.3 µM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-17 has the potential for the research of pancreatic, colorectal, and lung cancers[1].

Name	KRAS inhibitor-17

Description	KRAS inhibitor-17 (compound 3-9) is a potent KRAS G12C inhibitor with an IC50 of 3.37 µM. KRAS inhibitor-17 shows p-ERK inhibition activities with IC50s of 9.25, >33.3 µM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-17 has the potential for the research of pancreatic, colorectal, and lung cancers[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras
Target	KRas G12C:3.37 μM (IC50)
References	[1]. Brian alan, et al. KRAS g12c inhibitors and methods of using the same. WO2018119183 A2

Molecular Formula	C₂₁H₁₈Cl₂FN₃O₂S
Molecular Weight	466.36

KRAS inhibitor-17

Use of KRAS inhibitor-17

Names

KRAS inhibitor-17 Biological Activity

Chemical & Physical Properties