KRAS inhibitor-9
Modify Date: 2024-01-02 17:37:07
KRAS inhibitor-9 structure
|
Common Name | KRAS inhibitor-9 | ||
|---|---|---|---|---|
| CAS Number | 300809-71-6 | Molecular Weight | 292.807 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 492.4±55.0 °C at 760 mmHg | |
| Molecular Formula | C13H9ClN2S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 251.6±31.5 °C | |
Use of KRAS inhibitor-9KRAS inhibitor-9, a potent KRAS inhibitor (Kd=92 μM), blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 binds to KRAS G12D, KRAS G12C and KRAS Q61H protein with a moderate binding affinity. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSCLC cells with KRAS mutation but not normal lung cells. |
| Name | 4-(1,3-Benzothiazol-2-ylsulfanyl)-3-chloroaniline |
|---|---|
| Synonym | More Synonyms |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 492.4±55.0 °C at 760 mmHg |
| Molecular Formula | C13H9ClN2S2 |
| Molecular Weight | 292.807 |
| Flash Point | 251.6±31.5 °C |
| Exact Mass | 291.989563 |
| LogP | 4.85 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.772 |
| Hazard Codes | Xi |
|---|
| 4-(1,3-Benzothiazol-2-ylsulfanyl)-3-chloroaniline |
| Benzenamine, 4-(2-benzothiazolylthio)-3-chloro- |
| MFCD00227023 |
| 4-(Benzothiazol-2-ylsulfanyl)-3-chloro-phenylamine |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: KRAS inhibitor-9
- Price: Negotiable
- Purity: 99.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: KRAS inhibitor-9
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: KRAS inhibitor-9
- Price: $950.0/250mg $550.0/100mg $1750.0/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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