KRAS inhibitor-16

Modify Date: 2024-01-06 20:20:30

KRAS inhibitor-16 structure	Common Name	KRAS inhibitor-16
	CAS Number	2230873-67-1	Molecular Weight	452.33
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₆Cl₂FN₃O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of KRAS inhibitor-16

KRAS inhibitor-16 (compound 3-11) is a potent KRAS G12C inhibitor with an IC50 of 0.457 µM. KRAS inhibitor-16 shows p-ERK inhibition activities with IC50s of 3.06, 11.1 µM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-16 has the potential for the research of pancreatic, colorectal, and lung cancers[1].

Name	KRAS inhibitor-16

Description	KRAS inhibitor-16 (compound 3-11) is a potent KRAS G12C inhibitor with an IC50 of 0.457 µM. KRAS inhibitor-16 shows p-ERK inhibition activities with IC50s of 3.06, 11.1 µM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-16 has the potential for the research of pancreatic, colorectal, and lung cancers[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras
Target	KRas G12C:0.457 μM (IC50)
References	[1]. Brian Alan LANMAN, et al. Kras g12c inhibitors and methods of using the same. US20180334454A1.

Molecular Formula	C₂₀H₁₆Cl₂FN₃O₂S
Molecular Weight	452.33

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KRAS inhibitor-16

Use of KRAS inhibitor-16

Names

KRAS inhibitor-16 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.