BI-1408

Modify Date: 2024-01-13 23:03:41

Use of BI-1408

BI-1408 is a potent γ secretase modulator with an IC50 of 0.04 μM for Aβ42[1].

Name	BI-1408

Description	BI-1408 is a potent γ secretase modulator with an IC50 of 0.04 μM for Aβ42[1].
Related Catalog	Research Areas >> Neurological Disease
Target	IC50: 40 nM (Aβ42)[1]
References	[1]. Gerlach K, et al. Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators. Bioorg Med Chem. 2018 Jul 23;26(12):3227-3241.

Molecular Formula	C₂₂H₂₃FN₆
Molecular Weight	390.46