BTRX-335140(CYM-53093
Modify Date: 2024-01-10 12:39:55
BTRX-335140(CYM-53093 structure
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Common Name | BTRX-335140(CYM-53093 | ||
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| CAS Number | 2244614-14-8 | Molecular Weight | 453.55 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H32FN5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BTRX-335140(CYM-53093BTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively.BTRX-335140 endows with favorable in vitro ADMET and in vivo pharmacokinetic profiles and medication-like duration of action in rats. BTRX-335140 can distribute well into the CNS. ADMET (absorption, distribution, metabolism, excretion, and toxicity) [1]. |
| Name | BTRX-335140 |
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| Description | BTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively.BTRX-335140 endows with favorable in vitro ADMET and in vivo pharmacokinetic profiles and medication-like duration of action in rats. BTRX-335140 can distribute well into the CNS. ADMET (absorption, distribution, metabolism, excretion, and toxicity) [1]. |
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| Related Catalog | |
| Target |
IC50: 0.8 nM (κOR); 110 nM (μOR); 6500 nM (δOR)[1] |
| References |
| Molecular Formula | C25H32FN5O2 |
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| Molecular Weight | 453.55 |
| Storage condition | 2-8°C |