Propargyl-PEG11-methane

Modify Date: 2024-01-10 18:00:08

Propargyl-PEG11-methane Structure
Propargyl-PEG11-methane structure
Common Name Propargyl-PEG11-methane
CAS Number 2250411-18-6 Molecular Weight 554.67
Density N/A Boiling Point N/A
Molecular Formula C26H50O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG11-methane


Propargyl-PEG11-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG11-methane

 Propargyl-PEG11-methane Biological Activity

Description Propargyl-PEG11-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C26H50O12
Molecular Weight 554.67