Propargyl-PEG3-methane

Modify Date: 2024-01-16 19:08:01

Propargyl-PEG3-methane structure	Common Name	Propargyl-PEG3-methane
	CAS Number	89635-82-5	Molecular Weight	202.24800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₈O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Propargyl-PEG3-methane

Propargyl-PEG3-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]prop-1-yne
Synonym	More Synonyms

Description	Propargyl-PEG3-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₀H₁₈O₄
Molecular Weight	202.24800
Exact Mass	202.12100
PSA	36.92000
LogP	0.31580

m-PEG3-OH structure

m-PEG3-OH

CAS#:112-35-6

3-Bromopropyne structure

3-Bromopropyne

CAS#:106-96-7

~91%

Propargyl-PEG3-methane Structure

Propargyl-PEG3-...

CAS#:89635-82-5

Literature: Jervis, Peter J.; Moulis, Marie; Jukes, John-Paul; Ghadbane, Hemza; Cox, Liam R.; Cerundolo, Vincenzo; Besra, Gurdyal S. Carbohydrate Research, 2012 , vol. 356, p. 152 - 162

methoxytriethylenoxy propargyl ether

2,5,8,11-Tetraoxatetradec-13-yne

DC Chemicals Limited
China
Product Name: Propargyl-PEG4-methane
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: MPEG3-Propyne
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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