MAC glucuronide linker

Modify Date: 2025-08-25 08:02:22

MAC glucuronide linker structure	Common Name	MAC glucuronide linker
	CAS Number	2260960-07-2	Molecular Weight	990.82
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₃H₄₈BrN₃O₁₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MAC glucuronide linker

MAC glucuronide linker is a linker for antibody-drug-conjugations (ADCs) and is useful to prepare the MAC glucuronide SN-38 drug linker[1].

Name	MAC glucuronide linker

Description	MAC glucuronide linker is a linker for antibody-drug-conjugations (ADCs) and is useful to prepare the MAC glucuronide SN-38 drug linker[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Alkyl/ether
References	[1]. Lau UY, et al. Lactone Stabilization is Not a Necessary Feature for Antibody Conjugates of Camptothecins. Mol Pharm. 2018 Sep 4;15(9):4063-4072.

Molecular Formula	C₄₃H₄₈BrN₃O₁₇S
Molecular Weight	990.82
InChIKey	WMXFTIHCGUEXKO-SPDRDJHJSA-N
SMILES	COC(=O)C1OC(Oc2ccc(COC(=O)N(CBr)CCS(C)(=O)=O)cc2NC(=O)CN(C)C(=O)OCC2c3ccccc3-c3ccccc32)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O

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