MAC glucuronide phenol-linked SN-38

Modify Date: 2025-08-27 07:35:00

MAC glucuronide phenol-linked SN-38 structure	Common Name	MAC glucuronide phenol-linked SN-38
	CAS Number	2246380-69-6	Molecular Weight	1091.06
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₀H₅₄N₆O₂₀S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MAC glucuronide phenol-linked SN-38

pH-susceptible lactone (Drug linker 1) is a pH-susceptible lactone-linked SN-38 drug linker. pH-susceptible lactone is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively[1].

Name	pH-susceptible lactone

Description	pH-susceptible lactone (Drug linker 1) is a pH-susceptible lactone-linked SN-38 drug linker. pH-susceptible lactone is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> Drug-Linker Conjugates for ADC
References	[1]. Lau UY, et al. Lactone Stabilization is Not a Necessary Feature for Antibody Conjugates of Camptothecins. Mol Pharm. 2018 Sep 4;15(9):4063-4072.

Molecular Formula	C₅₀H₅₄N₆O₂₀S
Molecular Weight	1091.06

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

MAC glucuronide phenol-linked SN-38

Use of MAC glucuronide phenol-linked SN-38

Names

MAC glucuronide phenol-linked SN-38 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.