Ceftaroline FosaMil Inner salt
Modify Date: 2024-01-10 00:23:08
Ceftaroline FosaMil Inner salt structure
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Common Name | Ceftaroline FosaMil Inner salt | ||
|---|---|---|---|---|
| CAS Number | 229016-73-3 | Molecular Weight | 685.69300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H22N8O8PS4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Ceftaroline FosaMil Inner saltCeftaroline fosamil (TAK-599) inner salt, a cephalosporin derivative, is an N-phosphono prodrug of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil inner salt can be used for the research of MRSA infection[1][2][3]. |
| Name | ceftaroline fosamil |
|---|---|
| Synonym | More Synonyms |
| Description | Ceftaroline fosamil (TAK-599) inner salt, a cephalosporin derivative, is an N-phosphono prodrug of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil inner salt can be used for the research of MRSA infection[1][2][3]. |
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| Related Catalog | |
| In Vivo | Ceftaroline fosamil inner salt (s.c.) shows protective effects against experimental systemic infection caused by S. aureus N133 in mice, with ED50s of 1.60-2.37 mg/kg[1]. Ceftaroline fosamil inner salt (10 mg/kg; s.c.) disappeares rapidly and converts smoothly into T-91825 in blood of rats and monkeys[1]. |
| References |
| Molecular Formula | C22H22N8O8PS4 |
|---|---|
| Molecular Weight | 685.69300 |
| Exact Mass | 685.01800 |
| PSA | 344.02000 |
| LogP | 1.41980 |
| (6R,7R)-7-[[(2E)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[[4-(1-methylpyridin-1-ium-4-yl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| Pyridinium,4-[2-[[(6R,7R)-2-carboxy-7-[[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methyl-,inner salt |
| Ceftaroline FosaMil Inner salt |