Top Suppliers:I want be here
Related CAS#:
541-15-1 406-76-8
541-14-0 126372-70-1
6645-46-1 910825-21-7
1469900-95-5 3992-45-8
152064-94-3 14992-62-2
1508912-10-4 1527613-94-0
1499613-84-1 1515995-49-9
1529005-82-0 1540547-54-3
1515348-08-9 1540075-17-9
695186-84-6 1505013-01-3

541-15-1

541-15-1 structure
541-15-1 structure
  • Name: L-Carnitine inner salt
  • Chemical Name: (R)-carnitine
  • CAS Number: 541-15-1
  • Molecular Formula: C7H15NO3
  • Molecular Weight: 161.199
  • Catalog: API Digestive system medication Digestive drug
  • Create Date: 2018-02-05 08:00:00
  • Modify Date: 2025-08-20 09:36:21
  • L-carnitine is constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.Target: OthersL-Carnitine is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine can also be found in many foods, but red meats, such as beef and lamb, are the best choices for adding carnitine into the diet [1]. Administering L-carnitine (510 mg/day) to patients with the disease. L-carnitine treatment significantly improved the total time for dozing off during the daytime, calculated from the sleep logs, compared with that of placebo-treated periods. L-carnitine efficiently increased serum acylcarnitine levels, and reduced serum triglycerides concentration [2]. L-carnitine and its derivatives show promise in the treatment of chronic conditions and diseases associated with mitochondrial dysfunction but further translational studies are needed to fully explore their potential [3].
Name (R)-carnitine
Synonyms L-(-)-Carnitine
karnitin
ST 198
EINECS 208-768-0
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium Hydroxide Inner Salt
Carnitrine
USPorFCC
(R)-Carnitine
Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, hydroxide, inner salt, L-
L-CARNITIN
3-Hydroxy-4-(trimethylammonio)butanoate
g-Trimethylammonium-b-hydroxybutirate
CAR-OH
Vitamin BT
Monocamin
1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, inner salt
(-)-Carnitine
Carnitene
DL-Carnitine
(-)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate
carnitine (L-form)
(R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide inner salt
γ-Trimethyl-β-hydroxybutyrobetaine
Carnitine, (-)-
1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, inner salt, (2R)-
(R)-3-hydroxy-4-(trimethylammonio)butanoate
(-)-L-Carnitin
L(-)-Carnitine
Carnitine, L-
3-Hydroxy-4-trimethylammoniobutanoate
UNII:S7UI8SM58A
(L-3-Carboxy-2-hydroxypropyl)trimethylammonium hydroxide inner salt
Carnitine DL-form
L-Carnitine
BICARNESINE
Cardiogen
4-Copab
L-Carnitine inner salt
g-Trimethyl-b-hydroxybutyrobetaine
(3R)-3-Hydroxy-4-(trimethylammonio)butanoate
Levocarnitine
g-Amino-b-hydroxybutyric Acid Trimethylbetaine
MFCD00038747
(−)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate
D,L-carnitine
(±)-carnitine
Carniking
carnitine
Carnitor
Description L-carnitine is constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.Target: OthersL-Carnitine is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine can also be found in many foods, but red meats, such as beef and lamb, are the best choices for adding carnitine into the diet [1]. Administering L-carnitine (510 mg/day) to patients with the disease. L-carnitine treatment significantly improved the total time for dozing off during the daytime, calculated from the sleep logs, compared with that of placebo-treated periods. L-carnitine efficiently increased serum acylcarnitine levels, and reduced serum triglycerides concentration [2]. L-carnitine and its derivatives show promise in the treatment of chronic conditions and diseases associated with mitochondrial dysfunction but further translational studies are needed to fully explore their potential [3].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Marcovina, S.M., et al., Translating the basic knowledge of mitochondrial functions to metabolic therapy: role of L-carnitine. Transl Res, 2013. 161(2): p. 73-84.

[2]. Pekala, J., et al., L-carnitine--metabolic functions and meaning in humans life. Curr Drug Metab, 2011. 12(7): p. 667-78.

[3]. Miyagawa, T., et al., Effects of oral L-carnitine administration in narcolepsy patients: a randomized, double-blind, cross-over and placebo-controlled trial. PLoS One, 2013. 8(1): p. e53707.
Melting Point 197-212 °C(lit.)
Molecular Formula C7H15NO3
Molecular Weight 161.199
Exact Mass 161.105194
PSA 60.36000
LogP -4.52
Index of Refraction -32 ° (C=1, H2O)
Storage condition 2-8°C
Water Solubility 2500 g/L (20 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BP2980000
CHEMICAL NAME :
Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, hydroxide, inner salt, L-
CAS REGISTRY NUMBER :
541-15-1
LAST UPDATED :
199107
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H15-N-O3
MOLECULAR WEIGHT :
161.23
WISWESSER LINE NOTATION :
OV1YQ1K1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9 gm/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 35,645,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
7 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 63,558,1979
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS BP2980000
HS Code 29239000
HS Code 29239000
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Chemsrc provides CAS#:541-15-1 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 541-15-1 | Chemsrc address: https://m.chemsrc.com/en/baike/118533.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved