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541-15-1

541-15-1 structure
541-15-1 structure
  • Name: L-Carnitine inner salt
  • Chemical Name: (R)-carnitine
  • CAS Number: 541-15-1
  • Molecular Formula: C7H15NO3
  • Molecular Weight: 161.199
  • Catalog: API Digestive system medication Digestive drug
  • Create Date: 2018-02-05 08:00:00
  • Modify Date: 2026-07-01 07:49:11
  • L-carnitine is constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.Target: OthersL-Carnitine is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine can also be found in many foods, but red meats, such as beef and lamb, are the best choices for adding carnitine into the diet [1]. Administering L-carnitine (510 mg/day) to patients with the disease. L-carnitine treatment significantly improved the total time for dozing off during the daytime, calculated from the sleep logs, compared with that of placebo-treated periods. L-carnitine efficiently increased serum acylcarnitine levels, and reduced serum triglycerides concentration [2]. L-carnitine and its derivatives show promise in the treatment of chronic conditions and diseases associated with mitochondrial dysfunction but further translational studies are needed to fully explore their potential [3].

Name (R)-carnitine
Synonyms CNIFEED(R)
L-CNITIN
L-Cnitinete
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium Hydroxide Inner Salt
USPorFCC
AMMONIUM(3-CBOXY-2-HYDROXYPROPYL)TRIMETHYL-,HYDROXIDE
L-Cnitine 5th
VITAMIN B-GAMMA
3-Hydroxy-4-(trimethylammonio)butanoate
L-Cnipure(R) in water
Natrulon(R) RC-100
L(-)-CNITINE
Monocamin
Cniking
(-)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate
L-(-)-L-Cnitine
L-Cnitin blend
B-HYDROXY-GAMMA-TRIMETHYLAMINOBUTYRIC ACID
CNITINE, L
(R)-3-hydroxy-4-(trimethylammonio)butanoate
ME3-GAMMA-ABU(BETA-HYDROXY)-OH
LEVOCNITINE
D(+)-CNITINE
[(-)-BETA-HYDROXY-GAMMA-TRIMETHYLAMMONIO]BUTYRATE
(L-3-Carboxy-2-hydroxypropyl)trimethylammonium hydroxide inner salt
Carnitine DL-form
L-Cnitine, (R)-(-)-3-Hydroxy-4-(trimethylammonio)butyrate, Vitamin BT
Cardiogen
(-)-BETA-HYDROXY-GAMMA-TRIMETHYLAMINOBUTYRIC ACID INNER SALT
(3R)-3-Hydroxy-4-(trimethylammonio)butanoate
Cniking 50
Levocarnitine
BETA-HYDROXY-GAMMA-TRIMETHYLAMINOBUTYRIC ACID
Natrulon(R) RC-50DG
MFCD00038747
trimethylbetain
VITAMIN BT INNER SALT
LEVOCNITINE ORAL SOLUTION
D,L-carnitine
VITAMIN BT
Carnitor
Levocnitine WS
L-(-)-Carnitine
karnitin
ST 198
EINECS 208-768-0
L-3-hydroxy-4-butyrobetaine
L-CNITINE BASE
BICNESINE
Carnitrine
(2R)-3-Cboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium Inner Salt
(R)-Carnitine
L-CNITHINE
L-CARNITIN
(R)-3-HYDROXY-4-(TRIMETHYLAMMONIO)BUTYRATE
g-Trimethylammonium-b-hydroxybutirate
GAMMA-AMINO-BETA-HYDROXYBUTYRIC ACID TRIMETHYL BETAINE
CAR-OH
Vitamin BT
L-Cnipure(R) crystalline
1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, inner salt
(-)-Carnitine
Carnitene
L-CNITINE INNER SALT
DL-Carnitine
(R)-BETA-HYDROXY-GAMMA-(TRIMETHYLAMMONIO)BUTYRATE
gamma-Trimethylamino-beta-hydroxybutyrate
carnitine (L-form)
(R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide inner salt
γ-Trimethyl-β-hydroxybutyrobetaine
Natrulon RC
C-OH
(3-cboxy-2-hydroxypro
L-Cnitine Ttrate,L-cnitine,Vitamin BT,L-ca eatrnitine,L-ctheirrnitine
(-)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate, VitaminBT
L-CNITINE
(-)-L-Carnitin
CBOXY-N,N,N-TRIMETHYL-2-PROPEN-1-AMINIUMCHLORIDE
Cnitor
L(-)-Carnitine
Cnitene
3-Hydroxy-4-trimethylammoniobutanoate
UNII:S7UI8SM58A
(S)-3-Hydroxy-4-(trimethylammonio)butanoate
L-Carnitine
BICARNESINE
4-Copab
g-Trimethyl-b-hydroxybutyrobetaine
CNITINE, L-(AS)
D-CNITINE
L-CNITINE extrapure
g-Amino-b-hydroxybutyric Acid Trimethylbetaine
(−)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate
L-(3-Cboxy-2-hydroxypropyl)trimethyl Ammonium Hydroxide Inner Salt
CNIKING(R)
Ammonium, (3-cboxy-2-hydroxypropyl)trimethyl-, hydroxide, inner salt, L- (8CI)
(±)-carnitine
Carniking
L-Cnitine base SynonyMs 3-hydroxy-4-(triMethylaMMonio)butanoate
carnitine
Description L-carnitine is constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.Target: OthersL-Carnitine is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine can also be found in many foods, but red meats, such as beef and lamb, are the best choices for adding carnitine into the diet [1]. Administering L-carnitine (510 mg/day) to patients with the disease. L-carnitine treatment significantly improved the total time for dozing off during the daytime, calculated from the sleep logs, compared with that of placebo-treated periods. L-carnitine efficiently increased serum acylcarnitine levels, and reduced serum triglycerides concentration [2]. L-carnitine and its derivatives show promise in the treatment of chronic conditions and diseases associated with mitochondrial dysfunction but further translational studies are needed to fully explore their potential [3].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Marcovina, S.M., et al., Translating the basic knowledge of mitochondrial functions to metabolic therapy: role of L-carnitine. Transl Res, 2013. 161(2): p. 73-84.

[2]. Pekala, J., et al., L-carnitine--metabolic functions and meaning in humans life. Curr Drug Metab, 2011. 12(7): p. 667-78.

[3]. Miyagawa, T., et al., Effects of oral L-carnitine administration in narcolepsy patients: a randomized, double-blind, cross-over and placebo-controlled trial. PLoS One, 2013. 8(1): p. e53707.

Melting Point 197-212 °C(lit.)
Molecular Formula C7H15NO3
Molecular Weight 161.199
Exact Mass 161.105194
PSA 60.36000
LogP -4.52
Index of Refraction -32 ° (C=1, H2O)
Storage condition 2-8°C
Water Solubility 2500 g/L (20 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BP2980000
CHEMICAL NAME :
Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, hydroxide, inner salt, L-
CAS REGISTRY NUMBER :
541-15-1
LAST UPDATED :
199107
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H15-N-O3
MOLECULAR WEIGHT :
161.23
WISWESSER LINE NOTATION :
OV1YQ1K1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9 gm/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 35,645,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
7 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 63,558,1979
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS BP2980000
HS Code 29239000
HS Code 29239000
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