NQO1 substrate

Modify Date: 2025-08-25 17:24:20

NQO1 substrate Structure
NQO1 substrate structure
Common Name NQO1 substrate
CAS Number 2304503-05-5 Molecular Weight 268.18
Density N/A Boiling Point N/A
Molecular Formula C13H2F2N4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NQO1 substrate


NQO1 substrate acts as an efficient NQO1 substrate and may be a new option for the treatment of NQO1-overexpresssing drug-resistant NSCLC[1].

 Names

Name NQO1 substrate

 NQO1 substrate Biological Activity

Description NQO1 substrate acts as an efficient NQO1 substrate and may be a new option for the treatment of NQO1-overexpresssing drug-resistant NSCLC[1].
Related Catalog
References

[1]. Wu X, et al. Discovery of Nonquinone Substrates for NAD(P)H: Quinone Oxidoreductase 1 (NQO1) as Effective Intracellular ROS Generators for the Treatment of Drug-Resistant Non-Small-Cell Lung Cancer. J Med Chem. 2018 Dec 27;61(24):11280-11297.

 Chemical & Physical Properties

Molecular Formula C13H2F2N4O
Molecular Weight 268.18
InChIKey PZUSGRHVYDQLHR-UHFFFAOYSA-N
SMILES N#Cc1nc2c(nc1C#N)-c1cc(F)c(F)cc1C2=O
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