Proteasome Substrate II

Modify Date: 2023-01-20 17:57:52

Proteasome Substrate II Structure
Proteasome Substrate II structure
Common Name Proteasome Substrate II
CAS Number 348086-66-8 Molecular Weight 664.745
Density 1.3±0.1 g/cm3 Boiling Point 967.8±65.0 °C at 760 mmHg
Molecular Formula C35H44N4O9 Melting Point N/A
MSDS Chinese USA Flash Point 539.1±34.3 °C

 Use of Proteasome Substrate II


Z-Leu-Leu-Glu-AMC is a substrate peptide, and can be used for determination of postacidic-like hydrolysing activity of 20S proteasome[1]

 Names

Name z-leu-leu-glu-amc
Synonym More Synonyms

 Proteasome Substrate II Biological Activity

Description Z-Leu-Leu-Glu-AMC is a substrate peptide, and can be used for determination of postacidic-like hydrolysing activity of 20S proteasome[1]
Related Catalog
References

[1]. McNaught KS, et al. Proteasomal function is impaired in substantia nigra in Parkinson's disease. Neurosci Lett. 2001 Jan 19;297(3):191-4.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 967.8±65.0 °C at 760 mmHg
Molecular Formula C35H44N4O9
Molecular Weight 664.745
Flash Point 539.1±34.3 °C
Exact Mass 664.310852
PSA 193.14000
LogP 5.74
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.578

 Safety Information

Safety Phrases 22-24/25
WGK Germany 3

 Synonyms

Z-LEU-LEU-GLU-7-AMINO-4-METHYLCOUMARIN
Z-LLE-AMC
Z-ILE-AMC
N-[(Benzyloxy)carbonyl]-L-leucyl-L-leucyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-α-glutamine
Z-LEU-LEU-GLU-MCA
Cbz-Leu-Leu-Glu-AMC,Z-LLE-AMC
L-α-Glutamine, N-[(phenylmethoxy)carbonyl]-L-leucyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
Z-LEU-LEU-GLU-7-AMIDO-4-METHYLCOUMARIN
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