PAC1R antagonist 1

Modify Date: 2024-01-06 20:42:41

PAC1R antagonist 1 structure	Common Name	PAC1R antagonist 1
	CAS Number	2305204-24-2	Molecular Weight	372.81
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₇ClN₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PAC1R antagonist 1

PAC1R antagonist 1 (compound 3d) is a potent and orally active antagonist of PAC1 receptor. PAC1R antagonist 1 can inhibit pituitary adenylate cyclase-activating polypeptide (PACAP)- and nerve injury-induced allodynia[1].

Name	PAC1R antagonist 1

Description	PAC1R antagonist 1 (compound 3d) is a potent and orally active antagonist of PAC1 receptor. PAC1R antagonist 1 can inhibit pituitary adenylate cyclase-activating polypeptide (PACAP)- and nerve injury-induced allodynia[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Takasaki I, et, al. Synthesis of a novel and potent small-molecule antagonist of PAC1 receptor for the treatment of neuropathic pain. Eur J Med Chem. 2020 Jan 15;186:111902.

Molecular Formula	C₁₇H₁₇ClN₆O₂
Molecular Weight	372.81

PAC1R antagonist 1

Use of PAC1R antagonist 1

Names

PAC1R antagonist 1 Biological Activity

Chemical & Physical Properties