IDO1/TDO-IN-3

Modify Date: 2025-08-25 19:31:34

IDO1/TDO-IN-3 Structure
IDO1/TDO-IN-3 structure
Common Name IDO1/TDO-IN-3
CAS Number 2347579-03-5 Molecular Weight 345.69
Density N/A Boiling Point N/A
Molecular Formula C16H6ClF2N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IDO1/TDO-IN-3


IDO1/TDO-IN-3 is a potent inhibitor of IDO1/TDO. IDO1/TDO-IN-3 exhibits significant activities against IDO1 (IC50: 0.005 μM) and TDO (IC50: 0.004 μM). IDO1/TDO-IN-3 shows considerable in vivo anti-tumor activity and no obvious toxicity is observed[1].

 Names

Name IDO1/TDO-IN-3

 IDO1/TDO-IN-3 Biological Activity

Description IDO1/TDO-IN-3 is a potent inhibitor of IDO1/TDO. IDO1/TDO-IN-3 exhibits significant activities against IDO1 (IC50: 0.005 μM) and TDO (IC50: 0.004 μM). IDO1/TDO-IN-3 shows considerable in vivo anti-tumor activity and no obvious toxicity is observed[1].
Related Catalog
References

[1]. Pan S, et al. Discovery and structure-activity relationship studies of 1-aryl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives as potent dual inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1) and trytophan 2,3-dioxygenase (TDO). Eur J Med Chem. 2020 Dec 1;207:112703.

 Chemical & Physical Properties

Molecular Formula C16H6ClF2N3O2
Molecular Weight 345.69
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