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China
Product Name: 8-Gingerol
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 8-Gingerol
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DC Chemicals Limited
China
Product Name: 8-Gingerol
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 8-Gingerol
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Zhejiang Hangyu API Co., Ltd
China
Product Name: 8-GINGEROL
Price: ￥Inquiry/1kg
Purity: 99.5%
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23513-08-8

23513-08-8 structure

23513-08-8 structure

Name: 8-Gingerol
Chemical Name: [8]-Gingerol
CAS Number: 23513-08-8
Molecular Formula: C₁₉H₃₀O₄
Molecular Weight: 322.439
Catalog: Biochemical Chinese herbal medicine ingredients
Create Date: 2018-09-14 20:14:01
Modify Date: 2024-01-04 14:39:37
8-Gingerol, found in the rhizomes of ginger (Z. officinale) with oral bioavailability, activates TRPV1, with an EC50 of 5.0 µM. 8-Gingerol inhibits COX-2, and inhibits the growth of H. pylori in vitro[1][2].

Name	[8]-Gingerol
Synonyms	8-Gingerol (S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone 3-Dodecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)- (5s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)dodecan-3-one (5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone

Description	8-Gingerol, found in the rhizomes of ginger (Z. officinale) with oral bioavailability, activates TRPV1, with an EC50 of 5.0 µM. 8-Gingerol inhibits COX-2, and inhibits the growth of H. pylori in vitro[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Infection Research Areas >> Inflammation/Immunology
References	[1]. Dedov, V.N., et al. Gingerols: a novel class of vanilloid receptor (VR1) agonists. Br. J. Pharmacol. 137(6), 793-798 (2002). [2]. Chrubasik, S., et al. Zingiberis rhizoma: A comprehensive review on the ginger effect and efficacy profiles. Phytomedicine 12(9), 684-701 (2005).

Density	1.1±0.1 g/cm3
Boiling Point	476.4±35.0 °C at 760 mmHg
Melting Point	30 - 32 °C
Molecular Formula	C₁₉H₃₀O₄
Molecular Weight	322.439
Flash Point	162.6±19.4 °C
Exact Mass	322.214417
PSA	66.76000
LogP	3.55
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.517
Storage condition	2-8°C
Water Solubility	methanol: soluble1mg/mL, clear, colorless

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JR4362000

CHEMICAL NAME :: 3-Dodecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (S)-(+)-

CAS REGISTRY NUMBER :: 23513-08-8

LAST UPDATED :: 199503

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C19-H30-O4

MOLECULAR WEIGHT :: 322.49

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ZYZAEU Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. China) V.24- 1989- Volume(issue)/page/year: 25,231,1990

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H317
Precautionary Statements	P280
Hazard Codes	Xi: Irritant;
Risk Phrases	43
Safety Phrases	36/37
RIDADR	NONH for all modes of transport
WGK Germany	3.0
RTECS	JR4362000
HS Code	29145019

Precursor 9
1135-24-6 502-44-3 4547-43-7 1135-23-5
57371-44-5 1700-32-9 56024-44-3 69172-20-9
146830-53-7
DownStream 0