PROTAC IRAK4 degrader-3

Modify Date: 2024-01-12 21:48:28

PROTAC IRAK4 degrader-3 structure	Common Name	PROTAC IRAK4 degrader-3
	CAS Number	2374122-43-5	Molecular Weight	1086.28
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₇H₆₈FN₁₁O₈S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PROTAC IRAK4 degrader-3

PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader[1].

Name	PROTAC IRAK4 degrader-3

Description	PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> IRAK Research Areas >> Inflammation/Immunology Signaling Pathways >> PROTAC >> PROTAC Signaling Pathways >> Protein Tyrosine Kinase/RTK >> IRAK
Target	IRAK4
In Vitro	PROTAC IRAK4 degrader-3 (0.01~10 μM; 2 hours; PBMCs) mediated degradation is occurring in a proteasome dependent manner[1]. PROTAC IRAK4 degrader-3 (0.01~100 μM; 18 hours; PBMCs) is capable of completely blocking IL-6 secretion[1]. Western Blot Analysis[1] Cell Line: PBMCs Concentration: 0.01~10 μM Incubation Time: 2 hours Result: IRAK4 PROTAC-mediated degradation was occurring in a proteasome dependent manner.
References	[1]. Nunes J, et al. Targeting IRAK4 for Degradation with PROTACs. ACS Med Chem Lett. 2019;10(7):1081-1085. Published 2019 Jun 14.

Molecular Formula	C₅₇H₆₈FN₁₁O₈S
Molecular Weight	1086.28
Storage condition	2-8°C

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PROTAC IRAK4 degrader-3
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

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