TYK2 JH2-IN-1-d3

Modify Date: 2024-01-11 09:35:40

TYK2 JH2-IN-1-d3 Structure
TYK2 JH2-IN-1-d3 structure
 Common Name TYK2 JH2-IN-1-d3
CAS Number 2376999-19-6 Molecular Weight 508.52
Density N/A Boiling Point N/A
Molecular Formula C24H21D3FN9O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TYK2 JH2-IN-1-d3


TYK2?JH2-IN-1-d3 is the a deuterated, orally active and selective TYK2 inhibitor (compound 4h), targeting to JH2 domain (IC50=0.1 nM)[1].

 Names

Name TYK2 JH2-IN-1-d3

 TYK2 JH2-IN-1-d3 Biological Activity

Description TYK2?JH2-IN-1-d3 is the a deuterated, orally active and selective TYK2 inhibitor (compound 4h), targeting to JH2 domain (IC50=0.1 nM)[1].
Related Catalog
Target

TYK2 JH2 domain[1]

References

[1]. Xiao Z, et al. Structure-activity relationship study of central pyridine-derived TYK2 JH2 inhibitors: Optimization of the PK profile through C4' and C6 variations. Bioorg Med Chem Lett. 2023 Jul 15;91:129373.  

 Chemical & Physical Properties

Molecular Formula C24H21D3FN9O3
Molecular Weight 508.52
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Chemsrc provides TYK2 JH2-IN-1-d3(CAS#:2376999-19-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of TYK2 JH2-IN-1-d3 are included as well.>> amp version: TYK2 JH2-IN-1-d3

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