Bradykinin Fragment 1-7
Bradykinin Fragment 1-7 structure
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Common Name | Bradykinin Fragment 1-7 | ||
|---|---|---|---|---|
| CAS Number | 23815-87-4 | Molecular Weight | 756.84900 | |
| Density | 1.52 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C35H52N10O9 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of Bradykinin Fragment 1-7Bradykinin (1-7) is an amino-truncated Bradykinin peptide. Bradykinin (1-7) is a metabolite of Bradykinin, cleaved by endopeptidase. |
| Name | h-arg-pro-pro-gly-phe-ser-pro-oh acetate salt |
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| Synonym | More Synonyms |
| Description | Bradykinin (1-7) is an amino-truncated Bradykinin peptide. Bradykinin (1-7) is a metabolite of Bradykinin, cleaved by endopeptidase. |
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| Related Catalog | |
| In Vitro | The Bradykinin peptide system is a tissue-based system with potent cardiovascular and renal effects. To investigate the regulation of this system, a highly sensitive amino terminal-directed radioimmunoassay that, with high performance liquid chromatography, enables the measurement of Bradykinin-(1-7), Bradykinin-(1-8), and Bradykinin-(1-9), is developed. Together with a carboxy terminal-directed radioimmunoassay, Bradykinin peptides in rat kidney and blood are characterized. The predominant Bradykinin peptides in kidney are Bradykinin-(1-9) (~100 fmol/g wet weight of tissue) and Bradykinin-(1-7) (~70 fmol/g), with low levels of Bradykinin-(1-8) (~8 fmol/g) and Bradykinin-(4-9) (~12 fmol/g) detectable; Bradykinin-(2-9) and Bradykinin-(3-9) are below the limits of detection. In blood, the levels of Bradykinin-(1-9) are very low (~2 fmol/ml), and other Bradykinin peptides are below the limits ofdetection. Administration of the angiotensin converting enzyme (ACE) inhibitor Perindopril is associated with an approximate twofold increase in renal levels of Bradykinin-(1-8) and Bradykinin-(1-9) and a decrease in the Bradykinin-(1-7)/Bradykinin-(1-9) ratio. The amino terminal-directed radioimmunoassay is also applied to heart, aorta, brown adipose tissue, adrenal, lung, and brain. For these tissues, Bradykinin-(1-7) and Bradykinin-(1-9) are of similar abundance (16-340 fmol/g), with lower levels of Bradykinin-(1-8)[1]. |
| References |
| Density | 1.52 g/cm3 |
|---|---|
| Molecular Formula | C35H52N10O9 |
| Molecular Weight | 756.84900 |
| Exact Mass | 756.39200 |
| PSA | 293.68000 |
| Index of Refraction | 1.695 |
| Storage condition | −20°C |
| Water Solubility | Soluble in water (1 mg/ml). |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | F+ |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Ixodes scapularis: salivary kininase activity is a metallo dipeptidyl carboxypeptidase.
Exp. Parasitol. 89 , 213-21, (1998) Saliva and salivary gland homogenates of Ixodes scapularis contain a dipeptidyl carboxypeptidase activity that accounts for the previously described salivary kininase activity of this tick. Reversed p... |
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Bradykinin is not involved in angiotensin converting enzyme modulation of ovarian steroidogenesis and prostaglandin production in frog Rana esculenta.
Acta Physiol. Scand. 175 , 123-128, (2002) Angiotensin converting enzyme (ACE) was demonstrated to modulate the production of 17beta-estradiol, progesterone and prostaglandin E2 (PGE2) in frog ovary of Rana esculenta. However, the activity was... |
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Purification and characterization of bioactive peptides from skin extracts of Rana esculenta.
Biochim. Biophys. Acta 1033 , 318-323, (1990) The peptide fraction extracted by methanol from the skin of Rana esculenta, a species widely distributed in Western Europe, was investigated. The pharmacological activity found in the extract is attri... |
| des-phe(8)-des-arg(9)-bradykini |
| H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-OH |
| MFCD00076262 |
| BRADYKININ FRAGMENT 1-7 |
| BRADYKININ (1-7) |
| RPPGFSP |
| Arg-Pro-Pro-Gly-Phe-Ser-Pro-OH |
| bradykinin,des-Phe(8)-des-Arg(9) |
| ARG-PRO-PRO-GLY-PHE-SER-PRO ACETATE |
| BRADYKININ 1-7 ACETATE |
| ARG-PRO-PRO-GLY-PHE-SER-PRO |
| Bradykinin: 1-7 |
- GL Biochem (Shanghai) Ltd.
- China
- Product Name: Bradykinin: 1-7
- Price: $Inquiry/1kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Jackie Yang
- Taiwan Oyi peptide Co. Ltd
- China
- Product Name: Bradykinin Fragment 1-7
- Price: $Inquiry/1mg $Inquiry/100kg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Vinnie
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