OM-1700

Modify Date: 2025-08-27 08:54:07

OM-1700 Structure
OM-1700 structure
 Common Name OM-1700
CAS Number 2406276-78-4 Molecular Weight 458.49
Density N/A Boiling Point N/A
Molecular Formula C25H23FN6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of OM-1700


OM-1700 is a potent tankyrase inhibitor with IC50s of 127 and 14 nM for tankyrase 1 and tankyrase 2, respectively. OM-1700 reduces cell growth in the colon cancer cell line COLO 320DM (GI50=650 nM)[1].

 Names

Name OM-1700

 OM-1700 Biological Activity

Description OM-1700 is a potent tankyrase inhibitor with IC50s of 127 and 14 nM for tankyrase 1 and tankyrase 2, respectively. OM-1700 reduces cell growth in the colon cancer cell line COLO 320DM (GI50=650 nM)[1].
Related Catalog
Target

TNKS1:127 nM (IC50)

TNKS2:14 nM (IC50)

In Vitro OM-153 shows inhibition (IC50=19 nM) in a cellular (HEK293) WNT/β-catenin signaling reporter assay[1].
References

[1]. Leenders RGG, et al. Development of a 1,2,4-Triazole-Based Lead Tankyrase Inhibitor: Part II. J Med Chem. 2021;64(24):17936-17949.

 Chemical & Physical Properties

Molecular Formula C25H23FN6O2
Molecular Weight 458.49
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Chemsrc provides OM-1700(CAS#:2406276-78-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of OM-1700 are included as well.>> amp version: OM-1700

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