OM-1700
Modify Date: 2024-01-10 06:47:12
OM-1700 structure
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Common Name | OM-1700 | ||
|---|---|---|---|---|
| CAS Number | 2406276-78-4 | Molecular Weight | 458.49 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H23FN6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of OM-1700OM-1700 is a potent tankyrase inhibitor with IC50s of 127 and 14 nM for tankyrase 1 and tankyrase 2, respectively. OM-1700 reduces cell growth in the colon cancer cell line COLO 320DM (GI50=650 nM)[1]. |
| Name | OM-1700 |
|---|
| Description | OM-1700 is a potent tankyrase inhibitor with IC50s of 127 and 14 nM for tankyrase 1 and tankyrase 2, respectively. OM-1700 reduces cell growth in the colon cancer cell line COLO 320DM (GI50=650 nM)[1]. |
|---|---|
| Related Catalog | |
| Target |
TNKS1:127 nM (IC50) TNKS2:14 nM (IC50) |
| In Vitro | OM-153 shows inhibition (IC50=19 nM) in a cellular (HEK293) WNT/β-catenin signaling reporter assay[1]. |
| References |
| Molecular Formula | C25H23FN6O2 |
|---|---|
| Molecular Weight | 458.49 |