STING agonist-25
Modify Date: 2025-08-24 06:55:19
STING agonist-25 structure
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Common Name | STING agonist-25 | ||
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| CAS Number | 2408723-10-2 | Molecular Weight | 751.79 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C36H41N13O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of STING agonist-25STING agonist-25 (CF505) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING, increases phosphorylation of STING, TBK1 and IRF3. STING agonist-23 promotes the levels of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells. STING agonist-23 exhibits activity against SARS-CoV series strains[1]. |
| Name | STING agonist-25 |
|---|
| Description | STING agonist-25 (CF505) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING, increases phosphorylation of STING, TBK1 and IRF3. STING agonist-23 promotes the levels of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells. STING agonist-23 exhibits activity against SARS-CoV series strains[1]. |
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| Related Catalog | |
| In Vitro | STING agonist-25 (10 μM；3 小时或 5 小时) 处理 THP-1 细胞 3 小时后，增加磷酸化 STING、TBK1 和 IRF3 的水平；处理 THP-1 细胞 5 小时后，增加 IFN-β、IL-6、CXCL-10、TNF-α、ISG-15 和 CCL-5 的含量[1]。 |
| References |
| Molecular Formula | C36H41N13O6 |
|---|---|
| Molecular Weight | 751.79 |
| InChIKey | YQHIJJGKUAVQNL-BQYQJAHWSA-N |
| SMILES | CCn1nc(C)cc1C(=O)Nc1nc2cc(C(N)=O)cnc2n1CC=CCn1c(NC(=O)c2cc(C)nn2CC)nc2cc(C(N)=O)cc(OCCCO)c21 |