6'-GNTI dihydrochloride

Modify Date: 2024-01-10 17:56:21

6'-GNTI dihydrochloride Structure
6'-GNTI dihydrochloride structure
Common Name 6'-GNTI dihydrochloride
CAS Number 2410327-94-3 Molecular Weight 544.47
Density N/A Boiling Point N/A
Molecular Formula C27H31Cl2N5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 6'-GNTI dihydrochloride


6'-GNTI dihydrochloride, a κ-opioid receptor (KOR) agonist, displays bias toward the activation of G protein-mediated signaling over β-arrestin2 recruitment. 6'-GNTI 6'-GNTI dihydrochloride only activates the Akt pathway in striatal neurons[1].

 Names

Name 6'-GNTI dihydrochloride

 6'-GNTI dihydrochloride Biological Activity

Description 6'-GNTI dihydrochloride, a κ-opioid receptor (KOR) agonist, displays bias toward the activation of G protein-mediated signaling over β-arrestin2 recruitment. 6'-GNTI 6'-GNTI dihydrochloride only activates the Akt pathway in striatal neurons[1].
Related Catalog
References

[1]. Schmid CL, et al. Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at κ-opioid receptors in striatal neurons. J Biol Chem. 2013;288(31):22387-22398.

 Chemical & Physical Properties

Molecular Formula C27H31Cl2N5O3
Molecular Weight 544.47
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