CDK7-IN-11
Modify Date: 2024-04-05 22:09:25
CDK7-IN-11 structure
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Common Name | CDK7-IN-11 | ||
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| CAS Number | 2414896-32-3 | Molecular Weight | 488.60 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H28N6O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CDK7-IN-11CDK7-IN-11 is an orally active CDK7 inhibitor. CDK7-IN-11 exhibits high CDK7 inhibitory activity with IC50 value of 4.2 nM. CDK7-IN-11 can be effectively used for the research of diseases associated with CDK7[1]. |
| Name | CDK7-IN-11 |
|---|
| Description | CDK7-IN-11 is an orally active CDK7 inhibitor. CDK7-IN-11 exhibits high CDK7 inhibitory activity with IC50 value of 4.2 nM. CDK7-IN-11 can be effectively used for the research of diseases associated with CDK7[1]. |
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| Related Catalog | |
| Target |
CDK7:4.2 nM (IC50) |
| In Vitro | CDK7-IN-11 (example 5) has inhibitory activity for CDK7 with IC50 value of 4.2 nM[1]. CDK7-IN-11 (72 h) inhibits cell proliferation in MDA-MB-468 cells and HepG2 cells with IC50 values of 14.0 nM and 3.0 nM[1]. Cell Proliferation Assay[1] Cell Line: MDA-MB-468 cells, HepG2 cells Concentration: Incubation Time: 72 h Result: Showed antiproliferative effect in cells. |
| References |
[1]. Novel cdk7 inhibitory compound or pharmaceutically acceptable salt thereof. Patent. WO2021182914A1. |
| Molecular Formula | C26H28N6O2S |
|---|---|
| Molecular Weight | 488.60 |