MMP-2/9-IN-1

Modify Date: 2024-01-08 12:31:13

MMP-2/9-IN-1 structure	Common Name	MMP-2/9-IN-1
	CAS Number	2415311-84-9	Molecular Weight	441.29
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₆IN₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MMP-2/9-IN-1

MMP-2/9-IN-1 (Compound 4a) is a potent dual MMP-2 and MMP-9 inhibitor with IC50 values of 56 nM and 38 nM, respectively. MMP-2/9-IN-1 inhibits tumor growth, strongly induces cancer cell apoptosis, inhibits cell migration, and suppresses cell cycle progression leading to DNA fragmentation[1].

Name	MMP-2/9-IN-1

Description	MMP-2/9-IN-1 (Compound 4a) is a potent dual MMP-2 and MMP-9 inhibitor with IC50 values of 56 nM and 38 nM, respectively. MMP-2/9-IN-1 inhibits tumor growth, strongly induces cancer cell apoptosis, inhibits cell migration, and suppresses cell cycle progression leading to DNA fragmentation[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> MMP
Target	MMP-2:56 nM (IC50) MMP-9:38 nM (IC50)
References	[1]. Omar AM, et al. Novel molecular discovery of promising amidine-based thiazole analogues as potent dual Matrix Metalloproteinase-2 and 9 inhibitors: Anticancer activity data with prominent cell cycle arrest and DNA fragmentation analysis effects. Bioorg Chem. 2020 Aug;101:103992.

Molecular Formula	C₁₄H₁₆IN₇S
Molecular Weight	441.29

MMP-2/9-IN-1

Use of MMP-2/9-IN-1

Names

MMP-2/9-IN-1 Biological Activity

Chemical & Physical Properties