Trametenolic acid
Modify Date: 2024-01-11 12:57:46
Trametenolic acid structure
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Common Name | Trametenolic acid | ||
|---|---|---|---|---|
| CAS Number | 24160-36-9 | Molecular Weight | 456.70000 | |
| Density | 1.07±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C30H48O3 | Melting Point | 259-261 ºC | |
| MSDS | N/A | Flash Point | N/A | |
Use of Trametenolic acidTrametenolic acid is a lanostanol glycoside that isolated from the EtOH extract of the fruit bodies of Laetiporus versisporus[1]. |
| Name | (2R)-2-[(3S,5R,10S,13R,14R)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-enoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Trametenolic acid is a lanostanol glycoside that isolated from the EtOH extract of the fruit bodies of Laetiporus versisporus[1]. |
|---|---|
| Related Catalog | |
| Target |
ERK1 ERK2 |
| In Vitro | Trametenolic acid (1 mg/mL; 15-30 mins) induces the upregulation of autophagy-related proteins (Beclin-1, Atg12, and LC3) in B16-F1 cells by activating the ERK1/2 signaling pathway[1]. Trametenolic acid (1 mg/mL; 24 hours; B16-F1 cells) has dual synergic mechanisms to exert an anti-melanogenetic effect[1]. Trametenolic acid (0.1-4 mg/mL; 52 hours; B16-F1 cells) increase melanin synthesis by approximately 20% and 40% in cells transfected with siRNAs against mTOR and Atg5, respectively[1]. Western Blot Analysis[1] Cell Line: B16-F1 cells Concentration: 1 mg/mL Incubation Time: 15 and 30 mins Result: Increased the expression levels of phospho-p38, phospho-ERK1/2, Beclin-1, Atg12 and LC3 by approximately 46%, 10%, 48%, 126% and 49%, respectively. Western Blot Analysis[1] Cell Line: B16-F1 cells Concentration: 1 mg/mL Incubation Time: 24 hours Result: Increased the expression of ERK1/2 and p-ERK1/2 and decreased MITF, tyrosinase, and TRP 1 levels. |
| References |
| Density | 1.07±0.1 g/cm3 |
|---|---|
| Melting Point | 259-261 ºC |
| Molecular Formula | C30H48O3 |
| Molecular Weight | 456.70000 |
| Exact Mass | 456.36000 |
| PSA | 57.53000 |
| LogP | 7.54380 |
| Vapour Pressure | 3.26E-15mmHg at 25°C |
| Storage condition | 2-8℃ |
| Water Solubility | Insuluble (8.2E-6 g/L) (25 ºC) |
| Trametenolic acid |
| (+)-trametenolic acid B |
| Lanosta-8,24-dien-21-oic acid,3-hydroxy-,(3beta) |
| 3beta-Hydroxylanosta-8,24-dien-21-oic acid |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Trametenolic acid
- Price: Click To Check
- Purity: 95.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Trametenolic acid
- Price: ￥3438.0/5mg
- Purity: 98.0%
- Delivery: 2 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: Trametenolic acid
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 3β-Hydroxylanosta-8,24-dien-21-oic acid
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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